Super Methyl-SP™ supports methylation reactions, important for metabolism of homocysteine, by providing a combination of targeted nutrients and cofactors, such as trimethylglycine and MSM. This formula includes the antioxidant vitamins C and E, as well as high-potency riboflavin, vitamin B6, and vitamin B12. In addition, this formula includes a biologically active form of folate (5-methyltetrahydrofolic acid or 5-MTHF), which is normally produced and available to the body only at the final stage of the folate metabolic process.